摘要：

Trypsin is an ancient protease best known as a digestive enzyme in animals, and traditionally believed to be absent in plants and protists. A dinoflagellate bloom study we conducted in the Changjiang Estuary led us to question that notion. We found trypsin genes in diatoms were highly expressed before the dinoflagellate bloom and when environmental phosphorus concentration was declining. We then found that trypsin genes occur widely in different phyla of phytoplankton and throughout the global ocean. Our analysis further indicates that the expression of trypsin genes in diatoms is correlated with N and P nutrient conditions in the ocean. Furthermore, using CRISPR/Cas9 genome editing technology, we demonstrate that one of the trypsin genes in the model diatom Phaeodactylum tricornutum is a coordinate regulator of N and P nutrient homeostasis. This work advances our knowledge on the distribution of trypsin in the tree of life and reveals a new function of trypsin in phytoplankton, underscoring the need for further inquiries into evolutionary implications and ecological roles of trypsins in different groups of phytoplankton.  

個人簡介：

康涅狄格大學（美國）/廈門大學教授，美國科學促進會會士（AAAS Fellow），康涅狄格州科學院院士，湖沼與海洋科學學會會士（ASLO Fellow），藻類學會選舉委員會主任。歷任 Journal of Phycology，Frontiers in Microbiology等重要期刊的副主編或編委，在Science, PNAS等頂尖期刊發表學術論文200余篇，是國際上具有開拓性的海洋生態學領域知名學者。

騰訊會議：https://meeting.tencent.com/dm/Zpsn8C4TOnbn

會議ID：307-956-214